Description

1,3-Dipalmitoyl-2-(4-(Bis(2-Chloroethyl)Amino)Benzenebutanoyl)Glycerol is a synthetic, nitrogen mustard-functionalized glycerolipid compound. This specialized chemical is engineered for targeted delivery and controlled release applications, offering a unique mechanism of action. It is primarily utilized in advanced pharmaceutical research and development, particularly for creating novel prodrugs and targeted therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active component in the synthesis of novel anticancer prodrugs and targeted chemotherapeutic agents.
• Prodrug Design: Utilized in the development of lipophilic prodrugs designed for enhanced cellular uptake and site-specific activation.
• Lipid-based Drug Delivery Systems: Incorporated into liposomes, nanoparticles, and other lipid carriers to improve the pharmacokinetic profile and targeting of therapeutic payloads.
• Biochemical Research: Used as a tool compound in studies investigating lipid metabolism, cell signaling pathways, and the mechanisms of alkylating agents.
• Targeted Therapy Development: Explored for creating conjugates that selectively deliver cytotoxic nitrogen mustard groups to specific cell types or tissues.

Basic Information

Product Name	1,3-Dipalmitoyl-2-(4-(Bis(2-Chloroethyl)Amino)Benzenebutanoyl)Glycerol
CAS No.	85763-07-1
Molecular Formula	C53H92Cl2N1O6
Molecular Weight	910.18 g/mol
Synonyms	1,3-Dipalmitoyl-2-[4-[bis(2-chloroethyl)amino]benzoyloxybutyryl]glycerol; 2-[4-[Bis(2-chloroethyl)amino]benzoyloxybutyryl]-1,3-dipalmitoylglycerol; Glycerol 1,3-dipalmitate 2-[4-[bis(2-chloroethyl)amino]benzenebutanoate]; Nitrogen Mustard Glycerolipid Conjugate; Chlorambucil Glyceride Derivative; NSC 267220; 1,3-Dihexadecanoyl-2-[(4-{bis[2-(chloranyl)ethyl]amino}phenyl)carbonyloxybutanoyl]glycerol
EINECS	Contact for details

Quality Control

Our 1,3-Dipalmitoyl-2-(4-(Bis(2-Chloroethyl)Amino)Benzenebutanoyl)Glycerol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications such as assay (HPLC), related substances, and residual solvents, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a dry, cool, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.