Description

N(Sup 2)-(((2-Chloroethyl)Nitrosoamino)Carbonyl)-L-Lysyl-L-Prolyl-L-Valinamide Hydrochloride is a specialized synthetic peptide derivative of significant interest in advanced biochemical research and development. Its core value lies in its role as a key intermediate or reference standard for investigating enzyme inhibition and targeted therapeutic pathways. This compound is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on oncology and metabolic disease research. Its precise structure makes it a critical tool for developing novel diagnostic and therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a crucial intermediate or reference standard in the synthesis and study of novel therapeutic peptides and enzyme inhibitors.
• Biochemical Assay Development: Used as a substrate or inhibitor in enzymatic assays to study specific protease or kinase activity relevant to disease mechanisms.
• Oncology Research: Investigated for its potential role in targeted cancer therapy development due to its specific chemical modifications.
• Metabolic Disorder Studies: Applied in research models exploring enzyme pathways involved in various metabolic conditions.
• Peptide Chemistry: Acts as a building block or model compound for studying structure-activity relationships (SAR) in complex peptide synthesis.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental research in biochemistry and medicinal chemistry.
• Quality Control & Analytical Standards: Employed as a high-purity analytical reference standard for method validation and quality control in peptide manufacturing.

Basic Information

Product Name	N(Sup 2)-(((2-Chloroethyl)Nitrosoamino)Carbonyl)-L-Lysyl-L-Prolyl-L-Valinamide Hydrochloride
CAS No.	87230-64-6
Molecular Formula	C₂₀H₃₆ClN₇O₅ • HCl
Molecular Weight	534.91 g/mol
Synonyms	N(2)-(((2-Chloroethyl)nitrosoamino)carbonyl)-L-lysyl-L-prolyl-L-valinamide hydrochloride; L-Valinamide, N(2)-(((2-chloroethyl)nitrosoamino)carbonyl)-L-lysyl-L-prolyl-, hydrochloride; NSC 357756; Chloroethylnitrosocarbamoyl-Lys-Pro-Val-NH2 • HCl; CENU-Lys-Pro-Val-NH2 hydrochloride; Nitrosourea-peptide conjugate hydrochloride; (S)-2-(6-Amino-2-((S)-1-((S)-2-acetamido-3-methylbutanamido)pyrrolidine-2-carboxamido)hexanamido)-N-(2-chloroethyl)-N-nitrosocarboxamide hydrochloride
EINECS	Contact for details

Quality Control

Our N(Sup 2)-(((2-Chloroethyl)Nitrosoamino)Carbonyl)-L-Lysyl-L-Prolyl-L-Valinamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and NMR for structural verification, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (Mass Spectrometry)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.