β-Lactamase Inhibitors

Antibiotics

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β-Lactamase Inhibitors

β-Lactamase inhibitors are APIs designed to block bacterial β-lactamase enzymes that degrade β-lactam antibiotics, thereby restoring or enhancing antibiotic activity. These agents, including clavulanic acid, tazobactam, sulbactam, and novel non-β-lactam inhibitors, work by forming stable complexes with β-lactamases or irreversibly inactivating their catalytic sites. Their use significantly expands the spectrum of penicillins and cephalosporins against resistant pathogens producing TEM, SHV, CTX-M, or carbapenemase families. β-Lactamase inhibitors are essential in combination products to treat respiratory infections, urinary tract infections, intra-abdominal infections, and hospital-acquired resistant organisms. With rising antimicrobial resistance, next-generation inhibitors targeting metallo-β-lactamases and serine carbapenemases continue to be developed.

Cilastatin CAS NO 82009-34-5

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CAS No.:82009-34-5

Grade:Pharmacy Grade

Content:99.90%

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(5R,6R)-3-[(Dihydroxymethyl)Sulfinyl]-7-Oxo-6-[(S)-1-(Sulfooxy)Ethyl]-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid CAS NO 82138-66-7

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CAS No.:82138-66-7

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(3S)-3-[[(S)-2-Acetylamino-3-(4-Hydroxyphenyl)-1-Oxopropyl]Amino]-2-Oxo-1-Azetidinesulfonic Acid CAS NO 82144-71-6

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CAS No.:82144-71-6

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(3R)-3-[[(R)-2-Acetylamino-3-(4-Hydroxyphenyl)-1-Oxopropyl]Amino]-3-Methoxy-2-Oxo-1-Azetidinesulfonic Acid CAS NO 82227-66-5

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CAS No.:82227-66-5

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(5R,6S)-6-[(R)-1-Hydroxyethyl]-3-[[2-(Dimethylamino)-2-Iminoethyl]Thio]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid CAS NO 82922-60-9

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CAS No.:82922-60-9

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Bulgecin CAS NO 83930-18-1

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CAS No.:83930-18-1

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trans-2-[[[1-(2-Aminothiazol-4-Yl)-2-[(2-Methyl-4-Oxo-1-Sulphoazetidin-3-Yl)Amino]-2-Oxoethylidene]Amino]Oxy]-2-Methylpropionic Acid CAS NO 85506-30-5

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CAS No.:85506-30-5

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Content:99.90%

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6-Ethylidene-7-Oxo-3-Sulfo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid CAS NO 85618-29-7

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CAS No.:85618-29-7

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Content:99.90%

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