Description

1,3-dioxo-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindol-2(3H)-yl 2-(((4aR,6S,7R,8R,8aS)-7-acetamido-6-(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-yl)oxy)propanoate is a sophisticated chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex pharmaceutical molecules, particularly those with intricate carbohydrate or nucleoside-like architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutics, including antiviral agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of complex nucleoside analogs and carbohydrate-based active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the research and development of novel antiviral compounds targeting specific viral enzymes.
• Glycobiology Studies: Serves as a precursor or model compound in the study of glycosylation processes and carbohydrate-protein interactions.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value chiral molecules.
• Academic Research: Utilized in university and institutional labs for methodological development in asymmetric synthesis and protecting group chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	1,3-dioxo-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindol-2(3H)-yl 2-(((4aR,6S,7R,8R,8aS)-7-acetamido-6-(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-yl)oxy)propanoate
CAS No.	79734-49-9
Molecular Formula	C33H34N2O10
Molecular Weight	618.63 g/mol
Synonyms	N-Acetyl-6-O-benzyl-2-phenyl-1,3-dioxane-4,5-diyl acetal of 1,2-O-(1-methylethylidene)-α-D-glucofuranose derivative; 2-Phenyl-1,3-dioxane acetal glucofuranose derivative; Benzyl-protected glucofuranose acetal intermediate; (4aR,6S,7R,8R,8aS)-7-Acetamido-6-(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-yl 2-(1,3-dioxo-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindol-2(3H)-yl)propanoate; N-Acetyl-6-O-benzyl-2-phenyl-1,3-dioxane-4,5-diyl acetal; CAS 79734-49-9.
EINECS	Contact for details

Quality Control

Our 1,3-dioxo-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindol-2(3H)-yl 2-(((4aR,6S,7R,8R,8aS)-7-acetamido-6-(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-yl)oxy)propanoate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and chiral integrity, meeting the stringent requirements for advanced pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.