Description

2-[2-[2-[[6-amino-2-[1-[(2-amino-2-carbamoyl-ethyl)amino]-2-carbamoyl-ethyl]-5-methyl-pyrimidine-4-carbonyl]amino]-2-[[4-[[1-[[1-(5-amino-3,4-dihydroxy-6-methyl-oxan-2-yl)oxy-2-[4-[4-[3-(bis(2-hydroxyethyl)amino)propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]-2-hydroxy-ethyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]-3-hydroxy-butan-2-yl]carbamoyl]-1-(3H-imidazol-4-yl)ethoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate is a complex, high-purity biochemical intermediate of significant interest in advanced pharmaceutical research and development. Its intricate molecular architecture, featuring multiple functional groups, makes it a critical building block for synthesizing novel therapeutic agents. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of next-generation drugs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and targeted therapy research.
• Bioconjugation & Linker Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems due to its reactive sites suitable for conjugation.
• Enzyme Inhibitor Research: Acts as a scaffold or core structure for designing and testing novel enzyme inhibitors in biochemical assays.
• Peptidomimetic & Macrocyclic Compound Synthesis: Provides a structurally complex framework for creating peptidomimetics and macrocyclic compounds with potential therapeutic activity.
• High-Value Fine Chemical Production: Used in custom synthesis and contract manufacturing for producing specialized, low-volume, high-value chemical entities.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental research in medicinal chemistry and chemical biology.

Basic Information

Item	Detail
Product Name	2-[2-[2-[[6-amino-2-[1-[(2-amino-2-carbamoyl-ethyl)amino]-2-carbamoyl-ethyl]-5-methyl-pyrimidine-4-carbonyl]amino]-2-[[4-[[1-[[1-(5-amino-3,4-dihydroxy-6-methyl-oxan-2-yl)oxy-2-[4-[4-[3-(bis(2-hydroxyethyl)amino)propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]-2-hydroxy-ethyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]-3-hydroxy-butan-2-yl]carbamoyl]-1-(3H-imidazol-4-yl)ethoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate
CAS No.	77368-79-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Carbamic acid, (2R,3S,4R,5R)-2-[[(2R,3S,4R,5R)-5-[[2-[[4-[[1-[[1-[(5-amino-5-deoxy-2,3-di-O-methyl-β-D-glucopyranosyl)oxy]-2-[4-[4-[3-[bis(2-hydroxyethyl)amino]propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]-2-hydroxyethyl]carbamoyl]-2-hydroxypropyl]carbamoyl]-3-hydroxybutyl]carbamoyl]-1H-imidazol-4-yl]methoxy]-3,4-dihydroxyoxan-2-yl]methoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl ester; Complex Thiazole-Pyrimidine Glycoside Intermediate; Research Biochemical Intermediate 77368-79-7
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, LC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical R&D use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. Consider storing under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Assay	≥ 97.0% (by HPLC normalization)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.