Description

Mupirocin CAS NO 12650-69-0 is a potent, topically active antibiotic derived from *Pseudomonas fluorescens*. It is valued for its unique mechanism of action, specifically inhibiting bacterial isoleucyl-tRNA synthetase, which makes it highly effective against Gram-positive bacteria, including methicillin-resistant *Staphylococcus aureus* (MRSA). This product is essential for manufacturers in the pharmaceutical industry developing topical ointments, creams, and nasal formulations for treating primary skin infections and eliminating nasal carriage of MRSA.

Application

• Active Pharmaceutical Ingredient (API) in topical antibiotic ointments and creams.
• Key component in nasal formulations for the eradication of MRSA colonization.
• Used in veterinary pharmaceuticals for treating bacterial skin infections in animals.
• Formulation into medicated wound dressings and surgical preps.
• Research and development of novel antibiotic delivery systems.
• Manufacturing of over-the-counter (OTC) and prescription topical medications.

Basic Information

Product Name	Mupirocin
CAS No.	12650-69-0
Molecular Formula	C26H44O9
Molecular Weight	500.63 g/mol
Synonyms	Pseudomonic Acid A; Bactroban; Turixin; Pseudomonic Acid; (E)-(2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-Epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-β-methyl-2H-pyran-2-crotonic acid ester; 9-[[3-Methyl-1-oxo-4-[tetrahydro-3,4-dihydroxy-5-[[3-(2-hydroxy-1-methylpropyl)oxiran-2-yl]methyl]-2H-pyran-2-yl]but-2-enyl]oxy]nonanoic acid
EINECS	235-747-9

Quality Control

Our Mupirocin is manufactured under strict quality management systems and is compliant with major pharmacopeial standards. Each batch undergoes comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical use. Certificates of Analysis (COA) are provided and can be tailored to meet specific customer or regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm
Specific Rotation	-8.0° to -12.0° (c=1 in CHCl3)
Bacterial Endotoxins	< 0.25 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.