Description

Novobiocin Sodium Salt is a sodium salt derivative of the aminocoumarin antibiotic novobiocin, identified by CAS NO 1476-53-5. This compound is valued for its potent inhibitory activity against bacterial DNA gyrase, making it a critical biochemical tool in research and development. It is primarily sought by professionals in the pharmaceutical, biotechnology, and life sciences sectors for applications in antimicrobial research, enzyme studies, and as a selective agent in cell culture.

Application

• As a selective biochemical agent in microbiological and cell culture media to inhibit specific bacterial strains.
• Utilized in antibacterial mechanism of action studies, particularly targeting DNA gyrase (topoisomerase II).
• An important reference standard and analytical reagent in pharmaceutical quality control and research laboratories.
• Used in basic life science research to study bacterial resistance, protein synthesis, and antibiotic efficacy.
• Application in the development and validation of analytical methods such as HPLC for antibiotic detection.
• Potential use as a starting material or intermediate in the synthesis of novel antimicrobial compounds.

Basic Information

Product Name	Novobiocin Sodium Salt
CAS No.	1476-53-5
Molecular Formula	C31H35N2NaO11
Molecular Weight	634.61 g/mol
Synonyms	Albamycin Sodium; Cathomycin Sodium; Novobiocin Sodium; Streptonicate Sodium; Inamycin Sodium; Cardelmycin Sodium; Vulcamycin Sodium; (2S)-5,7-Dihydroxy-4-methyl-8-{[(1S,2S,3aS,9aR)-2-hydroxy-1-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-8-yl]carbamoyl}-2H-chromene-2-carboxylic acid sodium salt
EINECS	Contact for details

Quality Control

Our Novobiocin Sodium Salt is produced and tested under a rigorous quality management system. Each batch undergoes comprehensive analysis to ensure identity, purity, and potency meet high-grade standards suitable for research applications. A Certificate of Analysis (COA) detailing specific test results, including assay, related substances, and identification, is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and handled under appropriate conditions to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
pH (1% Solution)	6.0 - 8.0
Residue on Ignition	10.0% - 15.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.