Description

Ristomycin Monosulphate 91% is a semi-synthetic glycopeptide antibiotic derived from the natural product ristocetin. This high-purity grade is essential for research and development applications requiring a consistent and well-characterized reference standard. It is primarily utilized by pharmaceutical researchers and microbiologists in the study of bacterial cell wall synthesis and the development of novel antimicrobial agents. The product is supplied with comprehensive analytical documentation to ensure traceability and reliability for critical scientific work.

Application

• Antibiotic Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of new glycopeptide antibiotics.
• Microbiological Studies: Used in in vitro studies to investigate mechanisms of action against Gram-positive bacteria, particularly for understanding vancomycin-resistant strains.
• Biochemical Assays: Employed in enzymatic assays and binding studies related to bacterial cell wall precursor (D-Ala-D-Ala) interactions.
• Pharmaceutical Analysis: Acts as a certified reference material (CRM) for quality control and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical manufacturing.
• Academic Research: A critical tool for university and institutional labs studying antibiotic resistance, microbial physiology, and medicinal chemistry.

Basic Information

Item	Detail
Product Name	Ristomycin Monosulphate 91%
CAS No.	11006-74-9
Molecular Formula	C90H99Cl3N10O33S
Molecular Weight	~2067.2 g/mol
Synonyms	Ristomycin Monosulfate; Ristomycin A Monosulfate; Ristomycin Sulfate; Antibiotic PA 108A; Ristomycin; Ristocetin A (related compound); Spontin; Riston; Antibiotic 108A; Glycopeptide Antibiotic 108A
EINECS	Contact for details

Quality Control

Every batch of Ristomycin Monosulphate 91% is manufactured and tested under a strict quality management system. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC and spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for research-grade pharmaceutical intermediates and reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	91.0% min. (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details
Bacterial Endotoxins	< 1.0 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.