Description

Dihydrostreptomycin Sesquisulfate Salt is a semi-synthetic aminoglycoside antibiotic derived from streptomycin. This compound is valued for its broad-spectrum antibacterial activity, particularly against Gram-negative bacteria, and its enhanced stability profile compared to its parent molecule. It serves as a critical active pharmaceutical ingredient (API) and research biochemical for the pharmaceutical, veterinary medicine, and life science research sectors. Our supply ensures high purity and consistent quality for demanding industrial and laboratory applications.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of injectable antibiotic preparations.
• Veterinary pharmaceutical applications for the treatment of bacterial infections in livestock and poultry.
• Key component in microbiological culture media for selective inhibition of bacterial growth.
• Biochemical research reagent for studying bacterial protein synthesis and aminoglycoside mechanisms of action.
• Reference standard in analytical laboratories for quality control and method development.
• Intermediate in the synthesis of more complex antibiotic derivatives and conjugates.

Basic Information

Product Name	Dihydrostreptomycin Sesquisulfate Salt
CAS No.	1425-61-2
Molecular Formula	C21H41N7O12 · 1.5H2SO4
Molecular Weight	730.73 g/mol (free base)
Synonyms	Dihydrostreptomycin Sulfate; Streptomycin Dihydrogen Sulfate; DHS Sulfate; Dihydrostreptomycin Sesquisulfate; Antibiotic AY-5810; Dihydrostreptomycin Acid Sulfate; Dihydrostreptomycin Hemisulfate Salt; Dihydrostreptomycin Sesquisulphate
EINECS	215-850-8

Quality Control

Our Dihydrostreptomycin Sesquisulfate Salt is manufactured and tested under a strict quality management system. Each batch is analyzed to meet high-purity standards suitable for pharmaceutical and research use, with specifications covering identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, related substances, residual solvents, and microbiological quality. We support compliance with relevant pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0% (on dried basis)
pH (1% solution)	4.5 - 6.0
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Bacterial Endotoxins	Contact for details
Microbial Enumeration	Meets specified limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.