Description

Descarbamoylnovobiocin is a key chemical intermediate and reference standard derived from the antibiotic novobiocin. This compound is essential for pharmaceutical research and development, particularly in the study of antibiotic mechanisms and the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in antimicrobial drug discovery and analytical method development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis and structural modification of novobiocin and related antibiotic compounds.
• Biochemical Research: Used as a reference standard and tool compound in studies targeting DNA gyrase (GyrB subunit) and heat shock protein 90 (Hsp90).
• Antimicrobial Development: A vital starting material for research programs focused on developing new antibacterial agents with improved efficacy or reduced resistance.
• Analytical Standard: Employed in HPLC, LC-MS, and other analytical methods for the identification, quantification, and purity assessment of novobiocin-related substances.
• Academic Research: Utilized in university and institutional labs for fundamental studies in microbiology, enzymology, and medicinal chemistry.

Basic Information

Product Name	Descarbamoylnovobiocin
CAS No.	10544-02-2
Molecular Formula	C30H35NO9
Molecular Weight	553.60 g/mol
Synonyms	Descarbamoyl novobiocin; Novobiocin descarbamoyl; 3-[(2R,3S,4S,5R,6R)-4,5-Dihydroxy-6-methyl-3-[[(2S,3S,4R,5S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy]oxan-2-yl]oxy-8-methyl-2-oxo-4H-chromene-7-carboxylic acid; 7-Hydroxy-3-(4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido)-8-methyl-4-oxo-4H-chromene-2-carboxylic acid (related structural name); Antibiotic PA 93 descarbamoyl; Demethoxycarbonylnovobiocin
EINECS	Contact for details

Quality Control

Our Descarbamoylnovobiocin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.