Description

(2S)-3α-Vinyl-2β-(β-D-glucopyranosyloxy)-3,4-dihydro-4α-[[(2S,6S)-tetrahydro-6-[4-(4-hydroxyphenyl)-2-oxobutyl]-4-oxo-2H-pyran-2-yl]methyl]-2H-pyran-5-carboxylic acid methyl ester is a complex, high-purity glycosidic compound with a defined stereochemistry, serving as a critical advanced intermediate in pharmaceutical synthesis. Its intricate molecular architecture, featuring a glucopyranosyl moiety and a reactive vinyl group, makes it a valuable chiral building block for the development of novel therapeutic agents. This compound is primarily targeted at research and development laboratories and production facilities in the pharmaceutical and biotechnology sectors, where it is used in the synthesis of potential drug candidates, particularly in areas requiring sophisticated carbohydrate chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for complex glycosylated molecules.
• Medicinal Chemistry Research: Used as a building block in structure-activity relationship (SAR) studies and the synthesis of compound libraries for biological screening.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential drug candidates during process optimization and pilot-scale production.
• Glycobiology Studies: Serves as a specialized substrate or intermediate in research focused on glycosylation processes and carbohydrate-protein interactions.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	(2S)-3α-Vinyl-2β-(β-D-glucopyranosyloxy)-3,4-dihydro-4α-[[(2S,6S)-tetrahydro-6-[4-(4-hydroxyphenyl)-2-oxobutyl]-4-oxo-2H-pyran-2-yl]methyl]-2H-pyran-5-carboxylic acid methyl ester
CAS No.	74474-42-3
Molecular Formula	C31H38O12
Molecular Weight	602.63 g/mol
Synonyms	Methyl (2S)-3α-ethenyl-2β-(β-D-glucopyranosyloxy)-3,4-dihydro-4α-[[(2S,6S)-tetrahydro-6-[4-(4-hydroxyphenyl)-2-oxobutyl]-4-oxo-2H-pyran-2-yl]methyl]-2H-pyran-5-carboxylate; 3α-Vinyl-2β-(β-D-glucopyranosyloxy)-3,4-dihydro-4α-[[(2S,6S)-tetrahydro-6-[4-(4-hydroxyphenyl)-2-oxobutyl]-4-oxo-2H-pyran-2-yl]methyl]-2H-pyran-5-carboxylic acid methyl ester; CAS 74474-42-3; A glycosylated dihydropyran carboxylic acid ester derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and mass spectrometry for identity verification. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or cGMP guidelines for drug substance intermediates. Our commitment is to deliver material of consistent, high quality to support your critical development timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.