Description

.beta.-D-Allopyranoside, (3aS,4R,5R,6S,6aS)-2-(dimethylamino)-3a,5,6,6a-tetrahydro-6-hydroxy-4-(phenylmethoxy)methyl-4H-cyclopentoxazol-5-yl 2-deoxy-4-O-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-.beta.-D is a sophisticated, high-purity carbohydrate derivative and nucleoside analog building block. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on antiviral, anticancer, and other nucleoside-based drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex nucleoside analogs and prodrugs for antiviral and anticancer applications.
• Medicinal Chemistry Research: Serves as a critical building block for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Bioconjugation & Probe Development: Used in the preparation of labeled nucleosides for biochemical assays, diagnostic probes, and targeted drug delivery systems.
• Glycochemistry & Carbohydrate Research: Employed in the study of glycosylation reactions, enzyme inhibitors, and the synthesis of complex oligosaccharide mimetics.
• Process Development & Scale-up: Supports the optimization and scaling of synthetic routes from laboratory to pilot plant scale for clinical trial material production.

Basic Information

Item	Details
Product Name	.beta.-D-Allopyranoside, (3aS,4R,5R,6S,6aS)-2-(dimethylamino)-3a,5,6,6a-tetrahydro-6-hydroxy-4-(phenylmethoxy)methyl-4H-cyclopentoxazol-5-yl 2-deoxy-4-O-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-.beta.-D
CAS No.	186041-03-2
Molecular Formula	C43H43N3O11
Molecular Weight	777.82 g/mol
Synonyms	2'-Deoxy-2'-phthalimido-3'-O-benzyl-4',6'-O-benzylidene-β-D-allopyranoside derivative; Cyclopentoxazole nucleoside intermediate; Benzyl-protected allopyranoside phthalimide; Advanced nucleoside building block; CAS 186041-03-2; (3aS,4R,5R,6S,6aS)-2-(Dimethylamino)-3a,5,6,6a-tetrahydro-6-hydroxy-4-[(phenylmethoxy)methyl]-4H-cyclopenta[d]oxazol-5-yl 2-deoxy-4-O-[2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-β-D-allopyranoside]
EINECS	Contact for details

Quality Control

Our .beta.-D-Allopyranoside derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. All materials are characterized by advanced analytical techniques including HPLC, NMR, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.