Description

2H-Pyran-2-carboxylic acid, 6-[[(2R,3aR,5S,6S,7aS)-2-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]octahydro-1-[(2R)-2-[[(2R)-2-hydroxy-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-4-methyl-1-oxopentyl]-5-[(1-oxohexyl)oxy]-1H-indol-6-yl]oxy]tetrahydro-3,4,5-trihydroxy-, (2S,3S,4S,5S,6R)- is a complex, high-purity synthetic intermediate with a defined stereochemistry, designed for advanced research and development. This compound is critical for pharmaceutical chemists and biochemists working on the synthesis of novel, targeted therapeutic agents, particularly in the fields of oncology and metabolic disease. Its intricate structure, featuring multiple functional groups, makes it an essential building block for constructing sophisticated molecular architectures in drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of potential active pharmaceutical ingredients (APIs), especially for complex small-molecule drugs.
• Drug Discovery & Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to develop new therapeutic candidates with improved efficacy and selectivity.
• Biochemical Research: Employed as a tool compound or a labeled analog in proteomics and enzyme inhibition studies to investigate biological pathways.
• Peptidomimetic Synthesis: Acts as a sophisticated scaffold for creating peptide-like molecules with enhanced stability and bioavailability.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis for client-sponsored R&D projects requiring high-complexity intermediates.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in synthetic organic chemistry and chemical biology.

Basic Information

Product Name	2H-Pyran-2-carboxylic acid, 6-[[(2R,3aR,5S,6S,7aS)-2-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]octahydro-1-[(2R)-2-[[(2R)-2-hydroxy-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-4-methyl-1-oxopentyl]-5-[(1-oxohexyl)oxy]-1H-indol-6-yl]oxy]tetrahydro-3,4,5-trihydroxy-, (2S,3S,4S,5S,6R)-
CAS No.	1611990-01-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Contact for details. This is a complex, research-grade compound often referenced by its full systematic name or internal project codes. Common synonyms and abbreviations are available upon inquiry.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality management systems. We provide comprehensive analytical data to support your research, including HPLC purity, chiral purity confirmation, and structural verification via spectroscopic methods. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting identity, purity, and impurity profiles. Our quality commitment aligns with the standards expected for GMP-like non-clinical production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.