Description

(2S,3S,5R)-3-AZIDO-N-(3-((1S,2S,3S,5R,6R)-3,5-DIAZIDO-2-((2S,3R,4R,5S,6R)-3-AZIDO-6-(AZIDOMETHYL)-4,5-DIHYDROXYTETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLAMINO)PROPYL)-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-CARBOXAMIDE is a sophisticated, multi-functional nucleoside analog derivative designed for advanced research and development. This compound is of significant interest for its potential application in the synthesis of novel antiviral and anticancer agents, leveraging its unique azido-functionalized carbohydrate and nucleobase moieties. It serves as a critical building block for pharmaceutical researchers, medicinal chemists, and bioconjugation specialists working on next-generation therapeutics and diagnostic probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new therapeutic targets.
• Bioconjugation & Probe Development: The multiple azide groups enable efficient "click chemistry" (CuAAC) for labeling biomolecules, creating targeted imaging agents or drug delivery systems.
• Chemical Biology Tool: Employed to study nucleic acid metabolism and enzyme mechanisms within biological systems.
• Process Development: Serves as a reference standard or starting material for scaling up synthetic routes under GMP conditions.
• Academic Research: Used in universities and research institutes for fundamental studies in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	(2S,3S,5R)-3-Azido-N-(3-((1S,2S,3S,5R,6R)-3,5-diazido-2-((2S,3R,4R,5S,6R)-3-azido-6-(azidomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yloxy)-6-hydroxycyclohexylamino)propyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-carboxamide
CAS No.	948916-06-1
Molecular Formula	C30H42N20O11
Molecular Weight	834.79 g/mol
Synonyms	3'-Azido-3'-deoxythymidine (AZT) derivative, multi-azido nucleoside analog; Azidothymidine complex intermediate; 1-[(2S,4S,5S)-4-Azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione derivative; Click chemistry nucleoside scaffold; Thymidine azido derivative; CAS 948916-06-1; Polyazidated nucleoside
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality protocols. We provide comprehensive analytical data to support your research and development, ensuring reproducible results and supply chain integrity. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically including characterization by HPLC, NMR, and mass spectrometry. Our quality system is designed to meet the exacting standards of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent degradation due to its easily oxidized and light-sensitive nature. For long-term storage, desiccate to minimize exposure to moisture. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.