Description

[2S,(-)]-2β-(3-Furanyl)-1,4,4Aα,5,6,6A,9,10,10Aα,10B-Decahydro-6α,9α-Dihydroxy-6Aα,10Bβ-Dimethyl-4-Oxo-2H-Naphtho[2,1-C]Pyran-7-Carboxylic Acid Methyl Ester is a complex, high-purity synthetic intermediate characterized by its intricate polycyclic structure incorporating furan and naphthopyran motifs. This compound is of significant value in advanced pharmaceutical research and development, particularly for its potential as a key chiral building block. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and for medicinal chemistry studies.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) or anti-inflammatory pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities.
• Process Chemistry Development: Employed in the optimization of synthetic routes for scale-up, focusing on yield, purity, and stereochemical control.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Asymmetric Synthesis: Utilized in reactions that require specific stereochemistry, leveraging its defined [2S,(-)] configuration.
• Fine Chemical Synthesis: Acts as a starting material for the production of other specialized, high-value organic compounds.

Basic Information

Product Name	[2S,(-)]-2β-(3-Furanyl)-1,4,4Aα,5,6,6A,9,10,10Aα,10B-Decahydro-6α,9α-Dihydroxy-6Aα,10Bβ-Dimethyl-4-Oxo-2H-Naphtho[2,1-C]Pyran-7-Carboxylic Acid Methyl Ester
CAS No.	104901-06-6
Molecular Formula	C22H28O7
Molecular Weight	404.46 g/mol
Synonyms	Methyl (2S,4aR,6R,6aR,9R,10aR,10bR)-6,9-dihydroxy-2-(furan-3-yl)-4a,6a,10b-trimethyl-4-oxo-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-2H-naphtho[2,1-c]pyran-7-carboxylate; (2S)-2-(3-Furanyl)-1,4,4aα,5,6,6a,9,10,10aα,10b-decahydro-6α,9α-dihydroxy-6aα,10bβ-dimethyl-4-oxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester; 2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 1,4,4a,5,6,6a,9,10,10a,10b-decahydro-2-(3-furanyl)-6,9-dihydroxy-4a,6a,10b-trimethyl-4-oxo-, methyl ester, (2S,4aR,6R,6aR,9R,10aR,10bR)-; A complex diterpenoid derivative.
EINECS	Contact for details

Quality Control

Our [2S,(-)]-2β-(3-Furanyl)-1,4,4Aα,5,6,6A,9,10,10Aα,10B-Decahydro-6α,9α-Dihydroxy-6Aα,10Bβ-Dimethyl-4-Oxo-2H-Naphtho[2,1-C]Pyran-7-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.