Description

2H-Pyran-2-acetic acid, tetrahydro-2,4-dihydroxy-6-(1R)-1-(2S,5R,7S,8R,9S)-9-hydroxy-2,8-dimethyl-2-(2S,2R,3S,5R,5R)-octahydro-2-methyl-5-(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl-3-(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran- is a complex, high-purity chiral intermediate of significant interest in advanced organic synthesis. This compound is valued for its intricate stereochemistry and functional groups, which make it a critical building block for constructing sophisticated molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals where precise stereocontrol is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of complex drug candidates, particularly in oncology and anti-infective research.
• Advanced Organic Synthesis: Used as a specialized building block for constructing complex natural product analogs and macrocyclic compounds.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic methodologies.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of high-value target molecules.
• Chemical Biology Probes: Acts as a core structure for developing molecular probes to study biological pathways and enzyme functions.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2H-Pyran-2-acetic acid, tetrahydro-2,4-dihydroxy-6-(1R)-1-(2S,5R,7S,8R,9S)-9-hydroxy-2,8-dimethyl-2-(2S,2R,3S,5R,5R)-octahydro-2-methyl-5-(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl-3-(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-
CAS No.	119068-77-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	119068-77-8; (1R)-1-[(2S,5R,7S,8R,9S)-9-Hydroxy-2,8-dimethyl-2-[(2S,2'R,3S,5R,5'R)-octahydro-2'-methyl-5-[(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl]-3-(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]-1,6-dioxaspiro[4.5]dec-7-yl]-2,4-dihydroxytetrahydro-2H-pyran-6-acetic acid (IUPAC); Tetrahydro-2,4-dihydroxy-6-[(1R)-1-[(2S,5R,7S,8R,9S)-9-hydroxy-2,8-dimethyl-2-[(2S,2'R,3S,5R,5'R)-octahydro-2'-methyl-5-[(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl]-3-(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]-1,6-dioxaspiro[4.5]dec-7-yl]]-2H-pyran-2-acetic acid; CAS 119068-77-8.
EINECS	Contact for details

Quality Control

This high-value intermediate is manufactured under strict quality management systems, with process controls designed to ensure batch-to-batch consistency and stereochemical integrity. Each lot is subjected to comprehensive analytical characterization, including HPLC for purity and chiral methods to confirm enantiomeric excess. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under an inert atmosphere to preserve stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.