Description

(2S)-2-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethylsulfanylcarbonyl]propanoic acid is a sophisticated nucleotide-based biochemical building block, specifically a Coenzyme A (CoA) analog. This compound is critical for researchers and developers working on advanced enzymatic pathways and metabolic studies. It is primarily utilized in pharmaceutical research, biochemistry, and the development of novel diagnostic assays where precise modulation of acetyl-CoA-dependent processes is required.

Application

• Biochemical Research: As a key substrate or inhibitor in studies of acetyltransferase enzymes, including histone acetyltransferases (HATs) and other CoA-utilizing enzymes.
• Pharmaceutical Development: Serves as a critical intermediate or reference standard in the discovery and development of therapeutics targeting metabolic disorders, cancer, and neurodegenerative diseases.
• Diagnostic Assay Development: Used in the formulation of high-sensitivity enzymatic kits for clinical diagnostics and life science research.
• Enzymology Studies: Essential for kinetic studies, mechanism-of-action research, and profiling the activity of enzymes involved in acetylation reactions.
• Metabolomics & Proteomics: Acts as a chemical tool for labeling and tracking acetylation events in complex biological systems.

Basic Information

Product Name	(2S)-2-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethylsulfanylcarbonyl]propanoic acid
CAS No.	73173-91-8
Molecular Formula	C25H42N7O19P3S
Molecular Weight	869.62 g/mol
Synonyms	Acetyl Coenzyme A Lithium Salt; Acetyl-CoA; Acetyl CoA; S-Acetylcoenzyme A; CoASAc; AcCoA; Acetyl-Coenzyme A; Ace-CoA
EINECS	Contact for details

Quality Control

Our Acetyl Coenzyme A is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.