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[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-phosphonooxyoxolan-3-yl] hydrogen phosphate CAS NO 65331-78-4
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CAS No.:65331-78-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-phosphonooxyoxolan-3-yl] hydrogen phosphate is a high-purity nucleotide derivative essential for advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and reference standard in the study of nucleic acid metabolism and enzyme function. It is primarily required by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in the development of novel therapeutics and molecular biology tools.
Application
- Biochemical Research: Used as a substrate, inhibitor, or reference standard in enzymatic studies, particularly those involving kinases, polymerases, and other nucleic acid-metabolizing enzymes.
- Pharmaceutical R&D: Serves as a key intermediate or starting material in the synthesis of novel antiviral or anticancer nucleotide analogs.
- Diagnostic Reagent Manufacturing: Incorporated into high-sensitivity assay kits for the detection and quantification of specific enzymatic activities in clinical and research settings.
- Cell Signaling Studies: Applied in research focused on purinergic signaling pathways and intracellular energy metabolism.
- Reference Standard: Provides a certified standard for quality control and analytical method development in pharmaceutical and biotechnology laboratories.
Basic Information
| Product Name | [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-phosphonooxyoxolan-3-yl] hydrogen phosphate |
| CAS No. | 65331-78-4 |
| Molecular Formula | C20H26N10O14P2 |
| Molecular Weight | 692.42 g/mol |
| Synonyms | P1,P2-Bis(5'-adenosyl) triphosphate; Diadenosine triphosphate; Ap3A; Adenosine(5')triphospho(5')adenosine; 5'-Adenylyl triphospho-5'-adenosine; 1,N6-Etheno-2'-deoxy-2'-fluoroadenosine triphosphate (common research analog context); Bis(5'-adenosyl) triphosphate; P1,P2-Di(adenosine-5') triphosphate |
| EINECS | Contact for details |
Quality Control
Our [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-phosphonooxyoxolan-3-yl] hydrogen phosphate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry to ensure identity and potency. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with research-grade standards and support regulatory submissions.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Retention time corresponds to reference standard |
| Identification (NMR) | Spectrum consistent with structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 3.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Biological Activity | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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