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[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-phosphonooxyoxolan-3-yl] hydrogen phosphate CAS NO 65331-78-4


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CAS No.:65331-78-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-phosphonooxyoxolan-3-yl] hydrogen phosphate is a high-purity nucleotide derivative essential for advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and reference standard in the study of nucleic acid metabolism and enzyme function. It is primarily required by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in the development of novel therapeutics and molecular biology tools.

Application

  • Biochemical Research: Used as a substrate, inhibitor, or reference standard in enzymatic studies, particularly those involving kinases, polymerases, and other nucleic acid-metabolizing enzymes.
  • Pharmaceutical R&D: Serves as a key intermediate or starting material in the synthesis of novel antiviral or anticancer nucleotide analogs.
  • Diagnostic Reagent Manufacturing: Incorporated into high-sensitivity assay kits for the detection and quantification of specific enzymatic activities in clinical and research settings.
  • Cell Signaling Studies: Applied in research focused on purinergic signaling pathways and intracellular energy metabolism.
  • Reference Standard: Provides a certified standard for quality control and analytical method development in pharmaceutical and biotechnology laboratories.

Basic Information

Product Name [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-phosphonooxyoxolan-3-yl] hydrogen phosphate
CAS No. 65331-78-4
Molecular Formula C20H26N10O14P2
Molecular Weight 692.42 g/mol
Synonyms P1,P2-Bis(5'-adenosyl) triphosphate; Diadenosine triphosphate; Ap3A; Adenosine(5')triphospho(5')adenosine; 5'-Adenylyl triphospho-5'-adenosine; 1,N6-Etheno-2'-deoxy-2'-fluoroadenosine triphosphate (common research analog context); Bis(5'-adenosyl) triphosphate; P1,P2-Di(adenosine-5') triphosphate
EINECS Contact for details

Quality Control

Our [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-phosphonooxyoxolan-3-yl] hydrogen phosphate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry to ensure identity and potency. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with research-grade standards and support regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Retention time corresponds to reference standard
Identification (NMR) Spectrum consistent with structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 3.0%
Residual Solvents (GC) Meets ICH guidelines
Biological Activity Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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