Description

S-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (3S)-3-hydroxydecanethioate is a sophisticated nucleotide-based biochemical intermediate of significant interest in advanced pharmaceutical research and development. This compound's complex structure, featuring a modified adenosine moiety linked to a thioester chain, makes it a critical precursor for the synthesis of novel prodrugs and targeted therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing next-generation antiviral and anticancer therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of nucleotide prodrugs and antiviral compounds.
• Antiviral Drug Research: Used in the development of novel therapeutic agents targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a precursor for creating targeted cancer therapies that interfere with cellular nucleotide metabolism.
• Biochemical Probe Development: Utilized in research to study enzyme kinetics and metabolic pathways involving nucleotide analogs.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of high-value, complex active pharmaceutical ingredients (APIs).
• Metabolic Studies: Acts as a tool compound in pharmacological and toxicological studies to understand drug metabolism and disposition.

Basic Information

Item	Details
Product Name	S-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (3S)-3-hydroxydecanethioate
CAS No.	6245-70-1
Molecular Formula	C₃₀H₅₂N₇O₁₇P₃S
Molecular Weight	907.76 g/mol
Synonyms	[(2R)-4-[[[(2R,3R,5R)-5-(6-Aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]-L-alanyl-L-cysteinyl (3S)-3-hydroxydecanoate S-ester; Adenosine triphosphate derivative thioester; Modified ATP analog; Nucleotide-lipid conjugate; Research compound 6245-70-1; Custom nucleotide intermediate; Prodrug precursor 6245-70-1
EINECS	Contact for details

Quality Control

Our production of this high-purity biochemical adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural integrity and purity. Certificates of Analysis (COA) are provided with each shipment, detailing batch-specific results for identity, purity, and impurities. We support development under cGMP conditions where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.