Description

[[[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate is a high-purity, complex nucleotide derivative of significant biochemical importance. This compound serves as a critical building block and research reagent in advanced life science applications, particularly in the study of cellular energy metabolism and signaling pathways. It is essential for pharmaceutical R&D, academic research, and the development of diagnostic assays where precise molecular structure and activity are required.

Application

• Biochemical Research: As a key intermediate or substrate in enzymatic studies, particularly those involving kinases, phosphorylases, and other ATP-related metabolic pathways.
• Pharmaceutical Development: Used in the research and synthesis of novel drug candidates targeting metabolic disorders, cardiovascular diseases, and cancer.
• Diagnostic Reagent Manufacturing: A vital component in the formulation of high-sensitivity assay kits for measuring cellular energy status (e.g., ATP/ADP/AMP ratios) and enzyme activity.
• Enzymology Studies: Employed to investigate the mechanism and kinetics of enzymes that utilize or modify polyphosphate chains.
• Cell Signaling Research: Used to study purinergic signaling pathways and the role of extracellular nucleotides.
• Reference Standard: Serves as an analytical standard for quality control and method validation in pharmaceutical and biotechnology laboratories.

Basic Information

Product Name	[[[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
CAS No.	56983-23-4
Molecular Formula	C21H36N10O22P6
Molecular Weight	1002.37 g/mol
Synonyms	P1,P6-Di(adenosine-5') hexaphosphate; Diadenosine hexaphosphate; Ap6A; Adenosine-5' pentaphospho-5'-adenosine; Diadenosine-5',5'''-P1,P6-hexaphosphate; Di(adenosine-5')-hexaphosphate; 5'-Adenylyl (P5→5')adenosine P1,P6-hexaphosphate; 1,6-Bis(5'-adenosyl)hexaphosphate
EINECS	Contact for details

Quality Control

Our [[[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.