Description

S-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] 3-oxooctanethioate is a sophisticated, high-purity biochemical intermediate of significant interest in advanced pharmaceutical research and development. This compound matters as a critical building block for the synthesis of novel nucleotide-based therapeutics, offering researchers a precise tool for probing biological pathways and developing targeted treatments. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on oncology, virology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel nucleotide analogs and prodrugs for antiviral and anticancer applications.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and signal transduction mechanisms.
• Proteomics & Molecular Biology: Employed in the development of activity-based probes (ABPs) for labeling and studying specific enzyme classes.
• Drug Discovery: Integral to medicinal chemistry programs aimed at creating new chemical entities (NCEs) with modified pharmacokinetic properties.
• Preclinical Development: Utilized in the formulation and testing of experimental therapeutic candidates in animal models.

Basic Information

Product Name	S-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] 3-oxooctanethioate
CAS No.	54684-64-9
Molecular Formula	C₂₈H₄₇N₇O₁₇P₃S
Molecular Weight	902.70 g/mol
Synonyms	3-Oxooctanethioic acid S-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] ester; Adenosine triphosphate derivative; ATP analog intermediate; Nucleotide-lipid conjugate; Modified Coenzyme A precursor; Research biochemical 54684-64-9
EINECS	Contact for details

Quality Control

Our S-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] 3-oxooctanethioate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.