Description

S-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] prop-2-enethioate is a sophisticated, high-purity biochemical intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key building block in the synthesis of nucleotide analogs and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutics, particularly in areas such as antiviral and anticancer drug development.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleotide-based active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the development of prodrugs and nucleotide analogs targeting viral polymerases.
• Oncology Research: Serves as a precursor in the creation of chemotherapeutic agents that interfere with DNA/RNA synthesis.
• Biochemical Probe Development: Employed in the design of labeled or modified nucleotides for studying enzymatic mechanisms and cellular processes.
• Prodrug Synthesis: Utilized in constructing targeted prodrug molecules designed for enhanced cellular uptake and activation.
• High-Value Fine Chemical Production: A key raw material in the multi-step synthesis of complex, high-potency therapeutic candidates.

Basic Information

Product Name	S-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] prop-2-enethioate
CAS No.	5776-58-9
Molecular Formula	C24H39N7O16P3S
Molecular Weight	806.59 g/mol
Synonyms	9-[(2R,3S,4R,5R)-5-[[[[(2R)-3-[[2-[(2-Carboxyethyl)disulfanyl]ethyl]amino]-2-hydroxy-3-oxopropyl]amino]-hydroxyphosphoryl]oxymethyl]-3,4-dihydroxyoxolan-2-yl]-6-aminopurine; Adenosine derivative prodrug intermediate; S-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] 2-propenethioate; Nucleotide prodrug precursor
EINECS	Contact for details

Quality Control

This high-value biochemical is manufactured under strict quality control protocols suitable for research and pharmaceutical development. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and analytical data is provided with every shipment. Our quality system is designed to support regulatory filings and ensure batch-to-batch consistency for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.