Description

[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-[[[[3-[2-(2-hexanoylsulfanylethylcarbamoyl)ethylcarbamoyl]-3-hydroxy-2,2-dimethyl-propoxy]-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-oxolan-3-yl]oxyphosphonic acid CAS NO 5060-32-2 is a high-purity, chemically modified nucleotide analog designed for advanced research and development. This compound is critical for applications requiring precise biochemical modulation, particularly in the study of enzymatic pathways and cellular signaling. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active component in the synthesis of novel nucleoside-based therapeutics targeting viral infections and specific cancers.
• Biochemical Assay Development: Used as a substrate or inhibitor in enzymatic studies to investigate kinase, polymerase, or other nucleotide-binding protein functions.
• Proteomics and Molecular Biology: Employed in the design and synthesis of labeled probes for studying protein-nucleic acid interactions or cellular metabolism.
• Diagnostic Reagent Formulation: Acts as a critical raw material in the production of high-sensitivity diagnostic kits and assays.
• Antiviral & Anticancer Agent Discovery: Investigated for its potential as a lead compound or prodrug in new drug discovery pipelines.
• Life Science Tool Manufacturing: Supplied to manufacturers of research-grade biochemicals and kits for academic and industrial laboratories.

Basic Information

Product Name	[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-[[[[3-[2-(2-hexanoylsulfanylethylcarbamoyl)ethylcarbamoyl]-3-hydroxy-2,2-dimethyl-propoxy]-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-oxolan-3-yl]oxyphosphonic acid
CAS No.	5060-32-2
Molecular Formula	C27H45N8O16P3S
Molecular Weight	862.70 g/mol
Synonyms	Hexanoyl-CoA analog; Modified Adenosine Diphosphate Derivative; 5'-O-[{[[(3R)-3-Hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}amino)propyl]amino}butyl]oxy](hydroxy)phosphoryl}oxyphosphoryl]adenosine; Custom Nucleotide Probe; ATP Analog; Coenzyme A-linked Nucleotide; Research Biochemical 5060-32-2
EINECS	Contact for details

Quality Control

Our production of this high-value biochemical adheres to stringent quality protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. We provide comprehensive Certificates of Analysis (COA) detailing purity, impurity profiles, and analytical results. Quality management systems are in place to support cGMP standards for research and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.