Description

1,2-Cyclopentanediol, 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]nitrosoamino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)- is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters for its role as a critical building block in the synthesis of novel, targeted therapeutic agents, offering precise molecular architecture essential for drug efficacy and safety. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing next-generation small molecule drugs, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Oncology Drug Discovery: Used in the synthesis of targeted cancer therapies, leveraging its complex heterocyclic and fluorinated structure.
• Antiviral Agent Synthesis: Serves as a precursor in the development of potent antiviral compounds.
• Biochemical Research: Employed as a reference standard or probe in enzymatic and receptor binding studies.
• Precision Chemical Synthesis: Utilized in asymmetric synthesis and method development due to its multiple stereocenters and functional groups.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	1,2-Cyclopentanediol, 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]nitrosoamino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)-
CAS No.	2476859-55-7
Molecular Formula	C25H28F2N6O4S
Molecular Weight	546.59 g/mol
Synonyms	(1S,2S,3R,5S)-5-(2-Hydroxyethoxy)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]nitrosoamino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]cyclopentane-1,2-diol; 1,2-Cyclopentanediol derivative with triazolopyrimidine; Advanced Fluorinated Triazolopyrimidine Intermediate; Nitrosoamino Cyclopropane Pharmaceutical Building Block; CAS 2476859-55-7; (1S,2S,3R,5S)-Isomer of C25H28F2N6O4S; Propylthio-triazolopyrimidine cyclopentanediol.
EINECS	Contact for details

Quality Control

Our 1,2-Cyclopentanediol derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and pre-clinical development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ICH guidelines and can supply material tailored to specific project requirements, including research-grade and cGMP-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.