Description

2-Furyl-[4-[4-[[3-[2-Hydroxy-3-(Propan-2-Ylamino)Propoxy]Phenyl]Amino] -6,7-Dimethoxy-Quinazolin-2-Yl]Piperazin-1-Yl]Methanone Trihydrochloride is a high-purity, complex organic salt derivative of a quinazoline-based structure, designed for advanced research and development. This compound is of significant interest in pharmaceutical chemistry as a key intermediate or reference standard for the synthesis and study of targeted therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential kinase inhibitors and other targeted therapeutic compounds.
• Biochemical Research: Used as a reference standard or tool compound in enzymatic assays and pharmacological studies to investigate specific biological pathways.
• Drug Discovery & Development: Employed in hit-to-lead and lead optimization stages for the development of new chemical entities (NCEs) in oncology and other therapeutic areas.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) of quinazoline derivatives.
• Process Chemistry: Acts as a standard for developing and validating analytical methods (HPLC, LC-MS) for purity assessment in manufacturing processes.

Basic Information

Item	Detail
Product Name	2-Furyl-[4-[4-[[3-[2-Hydroxy-3-(Propan-2-Ylamino)Propoxy]Phenyl]Amino] -6,7-Dimethoxy-Quinazolin-2-Yl]Piperazin-1-Yl]Methanone Trihydrochloride
CAS No.	111218-84-9
Molecular Formula	C30H37Cl3N6O6
Molecular Weight	684.01 g/mol
Synonyms	2-Furyl-[4-[4-[[3-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]amino]-6,7-dimethoxy-2-quinazolinyl]-1-piperazinyl]methanone trihydrochloride; (2-Furyl){4-[4-({3-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}amino)-6,7-dimethoxyquinazolin-2-yl]piperazin-1-yl}methanone trihydrochloride; UNII-2H2M8X2Q4F; 2-Furyl(4-(4-((3-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)amino)-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)methanone trihydrochloride; A compound with CAS 111218-84-9
EINECS	Contact for details

Quality Control

Our 2-Furyl-[4-[4-[[3-[2-Hydroxy-3-(Propan-2-Ylamino)Propoxy]Phenyl]Amino] -6,7-Dimethoxy-Quinazolin-2-Yl]Piperazin-1-Yl]Methanone Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.