Description

2-Propenamide, N-[5-[[4-(1-cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-, compd. with methanesulfonate (1:1) is a high-purity, non-covalent small molecule inhibitor designed for advanced research and development. This compound is of significant interest for its targeted biological activity and serves as a critical building block in modern pharmaceutical discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical R&D Intermediate: Serves as a key synthetic precursor or active pharmaceutical ingredient (API) intermediate in the development of targeted therapies.
• Biochemical Research: Used as a selective tool compound in enzymatic and cellular assays to study specific biological pathways and mechanisms of action.
• Preclinical Studies: Employed in in vitro and in vivo studies to evaluate pharmacokinetics, pharmacodynamics, and efficacy profiles.
• High-Throughput Screening (HTS): Acts as a reference standard or a lead compound in screening libraries for drug discovery campaigns.
• Chemical Biology Probes: Utilized to design and synthesize probes for target identification and validation within complex biological systems.
• Process Chemistry Development: Supports route scouting and optimization for the scalable synthesis of complex drug candidates.

Basic Information

Product Name	2-Propenamide, N-[5-[[4-(1-cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-, compd. with methanesulfonate (1:1)
CAS No.	2134096-06-1
Molecular Formula	C₃₁H₃₈N₈O₂ • CH₄O₃S
Molecular Weight	Contact for details
Synonyms	N-[5-[[4-(1-Cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-2-propenamide methanesulfonate; (1:1) Methanesulfonate salt of a specific kinase inhibitor analog; Research Compound 2134096-06-1; Kinase Inhibitor Intermediate; Indole-pyrimidine based acrylamide derivative; Targeted small molecule inhibitor salt; Pharmaceutical intermediate CAS 2134096-06-1
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Our quality system includes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.