Description

1,2-Benzenediamine, 4-(3aS,4S,6R,6aR)-6-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-4H-1,3-dioxolo4,5-cpyrrol-4-yl-N,N,N,N-tetrakis(4-methoxyphenyl)methyl- is a sophisticated, high-purity chemical intermediate featuring a protected nucleoside analog structure. This compound is critical for enabling precise synthetic pathways in advanced research and development. It is primarily utilized by pharmaceutical and biotechnology companies engaged in the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex nucleoside analogs and related active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the development of prodrugs and nucleotide analogs targeting viral polymerases.
• Oncology Research: Serves as a precursor in the creation of novel chemotherapeutic agents and targeted cancer therapies.
• Bioconjugation & Probe Development: The reactive diamine and protected functional groups make it suitable for creating labeled probes for biochemical assays.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale production of specialty chemicals.
• Academic & Institutional Research: Used in laboratories for studying nucleic acid chemistry, enzyme mechanisms, and structure-activity relationships.

Basic Information

Product Name	1,2-Benzenediamine, 4-(3aS,4S,6R,6aR)-6-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-4H-1,3-dioxolo4,5-cpyrrol-4-yl-N,N,N,N-tetrakis(4-methoxyphenyl)methyl-
CAS No.	258834-81-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4-((3aS,4S,6R,6aR)-6-((tert-Butyldimethylsilyloxy)methyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrol-4-yl)-N,N,N,N-tetrakis(4-methoxyphenyl)methylbenzene-1,2-diamine; 4-(6-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-β-D-ribofuranosyl)-N,N,N,N-tetrakis(p-anisyl)methyl-o-phenylenediamine; Protected Nucleoside Diamine Intermediate; TBDMS-protected ribofuranosyl anisylphenylenediamine; CAS 258834-81-0.
EINECS	Contact for details

Quality Control

Our 1,2-Benzenediamine derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.