Description

[(2R,3R,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-2-[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-oxolan-3-yl]oxyphosphonic acid is a high-purity nucleotide derivative of significant importance in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and reference standard for studying nucleic acid metabolism, enzyme mechanisms, and for the synthesis of novel therapeutic agents. It is essential for researchers and manufacturers in the fields of antiviral drug development, molecular biology, and diagnostic assay production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analog prodrugs and antiviral compounds.
• Biochemical Research: Essential substrate or inhibitor for enzymatic studies involving polymerases, kinases, and other nucleic acid-modifying enzymes.
• Diagnostic Reagent Manufacturing: Used in the production of high-sensitivity kits for pathogen detection and genetic analysis.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method validation in pharmaceutical labs.
• Proteomics & Metabolomics: Employed in mass spectrometry as an internal standard for quantifying cellular nucleotides.
• Cell Culture & Media Supplement: Used in specialized cell culture applications to study nucleotide salvage pathways.

Basic Information

Item	Details
Product Name	[(2R,3R,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-2-[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-oxolan-3-yl]oxyphosphonic acid
CAS No.	24458-29-5
Molecular Formula	C19H25N8O14P2
Molecular Weight	663.40 g/mol
Synonyms	Deoxyadenosine monophosphate-uridine conjugate; dAMP-Uridine derivative; 2'-Deoxyadenosine 5'-(trihydrogen diphosphate), P'→5'-ester with uridine; Uridine-5'-[P1-(2'-deoxyadenosine-5')-P2-uridine-5']-diphosphate; Nucleotide dimer; dAMP-UMP; Adenine deoxyribonucleotide uridine monophosphate
EINECS	Contact for details

Quality Control

Every batch of our nucleotide derivatives is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting results from HPLC, NMR, and MS analysis. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and high-purity biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.