Description

N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7-(Acetyloxy)-13-hydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetren-2-yl]-2-oxopropanamide is a complex, high-purity macrolide derivative with significant biological activity. This compound is valued for its role as a critical intermediate in advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex macrolide-based active pharmaceutical ingredients (APIs).
• Biomedical Research: Used as a reference standard or probe compound in biochemical and pharmacological studies to investigate biological pathways.
• Drug Discovery: Serves as a core scaffold for medicinal chemistry programs aimed at developing new anti-infective or anti-cancer agents.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex molecular architectures with specific stereochemistry.
• Academic Research: Utilized in university and institutional labs for studying macrolide biosynthesis, structure-activity relationships (SAR), and chemical biology.

Basic Information

Product Name	N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7-(Acetyloxy)-13-hydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetren-2-yl]-2-oxopropanamide
CAS No.	23812-97-7
Molecular Formula	C28H35NO8
Molecular Weight	513.59 g/mol
Synonyms	2-Oxo-N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7-(acetyloxy)-13-hydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetraen-2-yl]propanamide; 7-O-Acetyl-12,13-bisepi-leukotriene C4; A derivative of Brefeldin A; (2S,3S,4R,5E,7S,9E,11E,13S,15R)-2-[(2S)-2-Hydroxy-1-oxopropyl]amino-3,4,15-trihydroxy-7-(acetyloxy)-13-methyl-5,9,11,17-octadecatetraenoic acid 17,18-lactone; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7-(Acetyloxy)-13-hydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetren-2-yl]-2-oxopropanamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.