Description

Kalafungin is a potent antifungal polyene macrolide antibiotic originally isolated from *Streptomyces tanashiensis*. This compound is of significant interest in pharmaceutical research and development due to its specific mechanism of action against fungal cell membranes. It serves as a critical reference standard and intermediate for researchers and manufacturers in the life sciences sector, particularly those focused on developing novel antifungal agents and studying microbial biochemistry.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in antifungal drug development and research.
• Biochemical Research: Serves as a key tool compound for studying the mechanism of action of polyene macrolides and fungal cell wall biosynthesis.
• Antifungal Agent Development: Acts as a lead compound or intermediate in the synthesis and development of new antifungal pharmaceuticals.
• Microbiology Studies: Employed in in-vitro assays to investigate fungal susceptibility and resistance patterns.

Basic Information

Product Name	Kalafungin
CAS No.	11048-15-0
Molecular Formula	C23H24O9
Molecular Weight	444.43 g/mol
Synonyms	Kalafungin; Antibiotic U 19,304; U-19304; U19,304; NSC 169505; (1R,2S,3S,4S,5R,8S,9S,10S,11S,12R,14S)-5-[(2S,4S,5S,6S)-4-Amino-5,6-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-ethyl-3,10,11,14-tetrahydroxy-2,8,12-trimethyl-9-oxotricyclo[7.4.0.0²,⁷]trideca-5,7-diene-13-carboxylic acid
EINECS	Contact for details

Quality Control

Our Kalafungin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.