Description

Nystatin CAS NO 1400-61-9 is a polyene antifungal antibiotic produced by *Streptomyces noursei*. It is a critical active pharmaceutical ingredient (API) valued for its potent fungistatic and fungicidal activity against a broad spectrum of Candida species and other yeasts. This compound is essential for manufacturers in the pharmaceutical, veterinary, and personal care industries, primarily for formulating topical and oral antifungal medications, creams, ointments, and powders.

Application

• Pharmaceutical Formulations: Primary API in topical creams, ointments, oral suspensions, and tablets for treating cutaneous, oral (thrush), and intestinal candidiasis.
• Veterinary Medicine: Used in medicated feeds, topical applications, and treatments for fungal infections in livestock, poultry, and companion animals.
• Personal Care & Cosmetics: Incorporated into antifungal powders, diaper rash creams, and intimate hygiene products to prevent yeast overgrowth.
• Agricultural Applications: Research and development of antifungal treatments for plant pathogens and post-harvest crop protection.
• Biomedical Research: Serves as a standard antifungal agent in microbiological laboratories for susceptibility testing and mechanistic studies.
• Industrial Preservation: Potential use as a preservative in specific industrial processes susceptible to yeast contamination, subject to regulatory approval.

Basic Information

Product Name	Nystatin
CAS No.	1400-61-9
Molecular Formula	C47H75NO17
Molecular Weight	926.09 g/mol
Synonyms	Nystatin A1; Fungicidin; Mycostatin; Nilstat; Biofanal; Diastatin; Moronal; Nystan; Nystavescent; Nystex; O-V Statin; Polyfungin; Stamicin
EINECS	215-748-2

Quality Control

Our Nystatin is manufactured and tested under strict quality management systems. We offer grades compliant with major pharmacopoeial standards, including USP and EP. Each batch undergoes rigorous analytical testing for identity, potency, purity, and microbiological quality. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment to ensure full traceability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 4400 U/mg (on dried basis)
Loss on Drying	≤ 6.0 %
pH (Suspension)	6.0 - 8.0
Heavy Metals	≤ 30 ppm
Total Impurities (HPLC)	≤ 5.0 %
Microbial Enumeration Tests	Meets USP/EP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.