Description

Amphotericin B, 8,9-Dideoxy-10-Hydroxy-7-Oxo- is a chemically modified derivative of the potent polyene macrolide antifungal agent, Amphotericin B. This compound is valued for its role as a critical intermediate in pharmaceutical research and development, particularly in the synthesis of novel antifungal agents with potentially improved therapeutic profiles. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on developing advanced anti-infective therapies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the chemical synthesis of novel antifungal drug candidates and analogs.
• Biomedical Research: Used in academic and industrial laboratories to study structure-activity relationships (SAR) of polyene antibiotics.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• API Development: Investigated in the development pathway for new Active Pharmaceutical Ingredients (APIs) targeting fungal infections.

Basic Information

Product Name	Amphotericin B, 8,9-Dideoxy-10-Hydroxy-7-Oxo-
CAS No.	1405-90-9
Molecular Formula	C47H73NO17
Molecular Weight	924.1 g/mol
Synonyms	8,9-Dideoxy-10-hydroxy-7-oxoamphotericin B; Amphotericin B Derivative; 7-Oxo-8,9-dideoxy-10-hydroxyamphotericin B; 7-Keto-8,9-dideoxy-10-hydroxyamphotericin B; Amphotericin B, 7-oxo-8,9-dideoxy-10-hydroxy-; 1405-90-9; Amphotericin B Impurity
EINECS	Contact for details

Quality Control

Our Amphotericin B, 8,9-Dideoxy-10-Hydroxy-7-Oxo- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label. Due to its light-sensitive and easily oxidized nature, prolonged exposure to light, air, or elevated temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.