Description

5-[[2-Amino-5-O-(aminocarbonyl)-2,3-dideoxy-L-erythro-pentonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxopyrimidin-1(2H)-yl]-β-D-allofuranuronic acid is a high-purity, complex nucleoside analog critical for advanced pharmaceutical research and development. This compound serves as a sophisticated building block and key intermediate in the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of next-generation nucleotide-based drugs, where precise chemical structure and purity are paramount for biological activity and regulatory approval.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and drug mechanisms of action.
• Antiviral Drug Development: Serves as a core structural component in the research of nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral agents.
• Oncology Research: Employed in the synthesis of experimental chemotherapeutic agents that target DNA/RNA synthesis in cancer cells.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Reference Standard: Functions as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5-[[2-Amino-5-O-(aminocarbonyl)-2,3-dideoxy-L-erythro-pentonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxopyrimidin-1(2H)-yl]-β-D-allofuranuronic acid
CAS No.	22976-88-1
Molecular Formula	C₁₆H₂₁N₅O₁₀
Molecular Weight	443.37 g/mol
Synonyms	1-(5-Carboxy-2,3,5-trideoxy-β-D-glycero-pent-2-enofuranosyl)-5-[(2-amino-5-O-carbamoyl-2,3-dideoxy-L-erythro-pentonoyl)amino]uracil; 5-[(2-Amino-5-O-carbamoyl-2,3-dideoxy-L-erythro-pentonoyl)amino]-1-(5-carboxy-2,3,5-trideoxy-β-D-glycero-pent-2-enofuranosyl)uracil; Carbocyclic Nucleoside Analog; L-Nucleoside Derivative; Uracil Carbocyclic Nucleoside; Advanced Nucleoside Intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-[[2-Amino-5-O-(aminocarbonyl)-2,3-dideoxy-L-erythro-pentonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxopyrimidin-1(2H)-yl]-β-D-allofuranuronic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data and full spectroscopic characterization are provided to guarantee traceability, consistency, and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.