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5-acetylamino-2-[[5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid CAS NO 22-12-8


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CAS No.:22-12-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-acetylamino-2-[[5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid is a complex nucleotide derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and research tool for studying nucleic acid metabolism, enzyme mechanisms, and for the synthesis of novel therapeutic agents. It is primarily sought by research institutions, biotechnology companies, and pharmaceutical developers working in the fields of antiviral drug discovery, molecular biology, and nucleotide chemistry. Its intricate structure makes it a valuable precursor for specialized biochemical applications.

Application

  • Pharmaceutical Intermediate: Key precursor in the research and synthesis of novel antiviral and anticancer nucleotide analogs.
  • Biochemical Research: Essential tool for studying DNA/RNA polymerase activity, nucleotide incorporation, and related enzymatic pathways.
  • Proteomics & Genomics: Used in the development of probes and labeled nucleotides for advanced sequencing and diagnostic applications.
  • Enzyme Inhibitor Studies: Serves as a substrate or inhibitor in mechanistic studies of kinases, transferases, and other nucleotide-processing enzymes.
  • Academic Research: Fundamental compound for university and institutional research exploring nucleotide chemistry and metabolism.
  • Reference Standard: High-purity material for use as an analytical standard in quality control laboratories for related pharmaceutical products.

Basic Information

Product Name 5-acetylamino-2-[[5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid
CAS No. 22-12-8
Molecular Formula Contact for details
Molecular Weight Contact for details
Synonyms N4-Acetylcytidine-5'-monophosphate derivative; Acetylated CMP analog; 5-Acetamido-cytidine monophosphate; N4-Acetylcytidine 5'-phosphate; 1-(5-O-Phosphono-β-D-ribofuranosyl)-N4-acetylcytosine; Complex Nucleotide Ester; Research Grade Nucleotide; Biochemical Building Block 22-12-8
EINECS Contact for details

Quality Control

Our 5-acetylamino-2-[[5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Assay ≥ 97.0%
Water Content (KF) ≤ 5.0%
Residual Solvents (GC) Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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