Description

(1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a-formyl-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl trifluoromethanesulfonate is a high-purity, advanced pharmaceutical intermediate featuring a reactive triflate ester group. This compound is a critical synthon for the targeted synthesis of complex steroid and terpenoid derivatives, enabling precise chemical modifications. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new bioactive compounds.
• Process Chemistry: Serves as a pivotal intermediate in the scalable production of complex natural product analogs.
• Organic Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) due to its reactive trifluoromethanesulfonate leaving group.
• Biochemical Research: Potential precursor for labeled compounds used in metabolic pathway studies.

Basic Information

Product Name	(1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a-formyl-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl trifluoromethanesulfonate
CAS No.	1449662-51-4
Molecular Formula	C₃₄H₄₇F₃O₄S
Molecular Weight	608.79 g/mol
Synonyms	3a-Formyl-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)octadecahydro-1H-cyclopenta[a]chrysen-9-yl triflate; Steroid Triflate Ester Intermediate; 9-Trifluoromethanesulfonyloxy Steroid Derivative; (1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-9-OTf Steroid; Trifluoromethanesulfonic acid (1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a-formyl-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)octadecahydro-1H-cyclopenta[a]chrysen-9-yl ester
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for research and development. Our products undergo rigorous testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.