Description

2,3,3,3-Tetrafluoropropionyl Chloride is a highly reactive fluorinated acid chloride derivative, serving as a critical building block for introducing the tetrafluoropropionyl moiety into complex molecules. Its primary value lies in enabling the synthesis of advanced materials and active pharmaceutical ingredients (APIs) with enhanced properties such as metabolic stability and lipophilicity. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: Key reagent for synthesizing fluorinated active pharmaceutical ingredients (APIs) and prodrugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides with improved efficacy.
• Liquid Crystal & OLED Materials: Building block for fluorine-containing compounds used in electronic display technologies.
• Polymer Modification: Imparts fluorinated characteristics to polymers, enhancing chemical resistance and surface properties.
• Organic Synthesis Reagent: Employed in acylations and as a precursor for other tetrafluoropropionic acid derivatives.
• Fluorinated Surfactant Production: Intermediate for creating high-performance, low-surface-tension surfactants.

Basic Information

Product Name	2,3,3,3-Tetrafluoropropionyl Chloride
CAS No.	1186-54-5
Molecular Formula	C3HF4ClO
Molecular Weight	164.49 g/mol
Synonyms	2,3,3,3-Tetrafluoropropanoyl Chloride; Perfluoropropionyl Chloride (common name); Tetrafluoropropanoyl Chloride; 2,3,3,3-Tetrafluoropropionic Acid Chloride; TFP-Cl; C3 Fluorinated Acid Chloride; 1186-54-5; NSC 92366
EINECS	214-685-6

Quality Control

Our 2,3,3,3-Tetrafluoropropionyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.