Description

Phenyl Chloroformate CAS NO 1885-14-9 is a versatile and highly reactive organic reagent, primarily used as a key building block in chemical synthesis. Its primary value lies in its role as a phenyloxycarbonylating agent, enabling the efficient introduction of the phenyl carbonate moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of carbonates, carbamates, and as a protecting group in complex organic transformations.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), especially for constructing carbonate and carbamate linkages found in various drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where phenyl carbonate structures are required.
• Polymer Chemistry: Serves as a monomer or modifying agent in the production of polycarbonates and other specialty polymers.
• Peptide & Protein Research: Employed as a protecting group for amino acids during solid-phase peptide synthesis (SPPS).
• Organic Synthesis Reagent: Utilized in laboratory-scale and industrial processes for esterification and carbonate formation reactions.
• Chemical Derivatization: Applied in analytical chemistry to derivative compounds for improved detection in chromatographic methods like HPLC.

Basic Information

Item	Details
Product Name	Phenyl Chloroformate
CAS No.	1885-14-9
Molecular Formula	C7H5ClO2
Molecular Weight	156.57 g/mol
Synonyms	Phenyl carbonochloridate; Chloroformic acid phenyl ester; Phenyl chlorocarbonate; Carbonic acid phenyl ester chloride; Phenyloxycarbonyl chloride; Benzyl chloroformate (common misnomer, but often searched); Carbonochloridic acid phenyl ester
EINECS	217-548-0

Quality Control

Our Phenyl Chloroformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for use as a fine chemical intermediate. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent and highly volatile compound, it should be kept under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent moisture ingress and decomposition. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Density	~1.25 g/cm³ at 20°C
Refractive Index	~1.510 at 20°C
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.