Description

CARBAMIC ACID, N-[2-[(R)-(3-CHLOROPHENYL)[(3R)-1-[[[(2S)-2-(METHYLAMINO)-3-[(3R)-TETRAHYDRO-2H-PYRAN-3-YL]PROPYL]AMINO]CARBONYL]-3-PIPERIDINYL]METHOXY]ETHYL]-, METHYL ESTER, 2,2,2-TRIFLUOROACETATE (1:1) is a high-purity, non-racemic chiral compound designed for advanced pharmaceutical research and development. This complex molecule serves as a critical intermediate or reference standard in the synthesis of novel therapeutic agents, particularly those targeting neurological and metabolic pathways. It is essential for pharmaceutical companies, contract research organizations (CROs), and academic research institutions engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs) with specific stereochemistry.
• Drug Discovery Research: Used as a reference standard or precursor in high-throughput screening and structure-activity relationship (SAR) studies for central nervous system (CNS) targets.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of candidate drugs.
• Analytical Reference Material: Serves as a certified standard for method development and validation in quality control (QC) laboratories using HPLC, LC-MS, or chiral analysis.
• Biochemical Research: Potential tool compound for investigating enzyme inhibition or receptor binding assays due to its specific structural motifs.

Basic Information

Product Name	CARBAMIC ACID, N-[2-[(R)-(3-CHLOROPHENYL)[(3R)-1-[[[(2S)-2-(METHYLAMINO)-3-[(3R)-TETRAHYDRO-2H-PYRAN-3-YL]PROPYL]AMINO]CARBONYL]-3-PIPERIDINYL]METHOXY]ETHYL]-, METHYL ESTER, 2,2,2-TRIFLUOROACETATE (1:1)
CAS No.	1013937-63-7
Molecular Formula	C27H40ClF3N4O6
Molecular Weight	609.08 g/mol
Synonyms	(2S)-N-Methyl-1-[(3R)-3-[[(2R)-2-[[(3-Chlorophenyl)[2-[(methoxycarbonyl)amino]ethoxy]methyl]piperidin-1-yl]carbonyl]amino]-3-(tetrahydro-2H-pyran-3-yl)propyl]amine 2,2,2-Trifluoroacetate; UNII-9K3E6V6M4B; 9K3E6V6M4B; (2S)-N-Methyl-1-[(3R)-3-[[(2R)-2-[[(3-Chlorophenyl)[2-[(methoxycarbonyl)amino]ethoxy]methyl]piperidin-1-yl]carbonyl]amino]-3-(tetrahydropyran-3-yl)propyl]amine TFA Salt; Carbamic acid, N-[2-[(R)-(3-chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]-, methyl ester, 2,2,2-trifluoroacetate (1:1)
EINECS	Contact for details

Quality Control

Our CARBAMIC ACID, N-[2-[(R)-(3-CHLOROPHENYL)[(3R)-1-[[[(2S)-2-(METHYLAMINO)-3-[(3R)-TETRAHYDRO-2H-PYRAN-3-YL]PROPYL]AMINO]CARBONYL]-3-PIPERIDINYL]METHOXY]ETHYL]-, METHYL ESTER, 2,2,2-TRIFLUOROACETATE (1:1) is manufactured under cGMP-compliant conditions suitable for pharmaceutical research. Each batch undergoes rigorous analytical testing to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, chiral purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.