Description

3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-, Mono[(6R-trans)-3-[(acetyloxy)Methyl]-7-aMino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] (9CI) CAS NO 191470-04-9 is a sophisticated, high-purity chemical intermediate of significant importance in advanced pharmaceutical synthesis. Its complex molecular architecture, featuring a fused quinoline and β-lactam core, makes it a critical building block for the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the discovery and production of next-generation antibacterial agents and other specialized therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel fluoroquinolone and cephalosporin hybrid antibiotics.
• Active Pharmaceutical Ingredient (API) Research: Used as a core scaffold in medicinal chemistry for designing new molecules with targeted biological activity.
• Biochemical Research: Employed in studies investigating structure-activity relationships (SAR) and mechanism of action for antibacterial compounds.
• Process Development: Utilized in scaling up and optimizing synthetic routes for complex drug candidates in pilot plants and commercial manufacturing.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical development.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-, Mono[(6R-trans)-3-[(acetyloxy)Methyl]-7-aMino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] (9CI)
CAS No.	191470-04-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid compound with (6R,7R)-7-amino-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Ciprofloxacin Cephalosporin Ester; Ciprofloxacin Acylated with 7-ACA derivative; Fluoroquinolone-Cephalosporin Conjugate Intermediate; Antibacterial Hybrid Intermediate; (6R-trans)-3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid compound with 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-ethyl-1-piperazinyl)-3-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict cGMP (current Good Manufacturing Practice) guidelines to ensure batch-to-batch consistency and traceability. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and Mass Spectrometry to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.