Description

(4R)-4-[(3R,4R,5S,8R,9S,10R,12S,13R,14S,17R)-3,4,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid is a high-purity, complex steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral building block and intermediate for synthesizing novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation steroid-based drugs and reference standards.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel steroid-based active pharmaceutical ingredients (APIs) and prodrugs.
• Research & Development: Used as a reference standard and building block in medicinal chemistry for drug discovery programs targeting hormone receptors.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and metabolic processes.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of specialized steroid analogs with modified biological activity.
• Analytical Standard: Provides a high-purity compound for method development and quality control in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	(4R)-4-[(3R,4R,5S,8R,9S,10R,12S,13R,14S,17R)-3,4,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
CAS No.	129012-50-6
Molecular Formula	C24H38O5
Molecular Weight	406.56 g/mol
Synonyms	17β-[(1R)-1-Carboxy-3-methylbutyl]estr-5-ene-3β,4β,12β-triol; 3β,4β,12β-Trihydroxy-17β-[(1R)-1-carboxy-3-methylbutyl]estr-5-ene; (4R)-4-[(3R,4R,5S,8R,9S,10R,12S,13R,14S,17R)-3,4,12-Trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid; A Steroid Carboxylic Acid Derivative; CAS 129012-50-6
EINECS	Contact for details

Quality Control

Our (4R)-4-[(3R,4R,5S,8R,9S,10R,12S,13R,14S,17R)-3,4,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, NMR, and MS for structural confirmation, to ensure it meets the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.