Description

4-Pregnene-17,20Beta,21-Triol-3-One is a high-purity steroid intermediate of significant importance in pharmaceutical synthesis. This compound serves as a critical building block for the production of more complex corticosteroid and progestogen derivatives. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of corticosteroid drugs such as hydrocortisone and its analogs.
• Research & Development: Used in biochemical and pharmacological research to study steroid metabolism and receptor interactions.
• API Manufacturing: Employed in multi-step synthesis processes for the commercial production of steroidal active pharmaceutical ingredients.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Utilized in scaling up synthetic routes and optimizing manufacturing processes for steroidal compounds.

Basic Information

Product Name	4-Pregnene-17,20Beta,21-Triol-3-One
CAS No.	128-19-8
Molecular Formula	C21H32O4
Molecular Weight	348.48 g/mol
Synonyms	11-Deoxycortisol; 17,21-Dihydroxypregn-4-ene-3,20-dione; Cortexolone; Reichstein's Substance S; 17α,21-Dihydroxypregn-4-ene-3,20-dione; 4-Pregnene-17α,21-diol-3,20-dione; 11-Deoxy-17-hydroxycorticosterone
EINECS	204-879-5

Quality Control

Our 4-Pregnene-17,20Beta,21-Triol-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.