Description

Pregnenolone CAS NO 145-13-1 is a fundamental steroid hormone and a crucial biochemical precursor in the synthesis of numerous other steroid hormones, including progesterone, cortisol, and DHEA. Its role as a key metabolic intermediate makes it essential for research and development in the life sciences. This compound is primarily utilized by the pharmaceutical, nutraceutical, and research sectors for the development of therapeutic agents, reference standards, and in-depth metabolic studies.

Application

• Pharmaceutical Intermediate: A critical starting material for the synthesis of a wide range of steroid-based drugs, including corticosteroids, sex hormones, and neurosteroids.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of pharmaceutical products and biological samples via HPLC, GC-MS, or LC-MS.
• Biochemical Research: Employed in academic and industrial research to study steroidogenesis, neurosteroid activity, hormone regulation, and related metabolic pathways.
• Nutraceutical Ingredient: Serves as a raw material in the formulation of dietary supplements targeting hormonal balance, cognitive function, and wellness.
• Cosmetic Science: Investigated for potential applications in topical formulations aimed at skin health and anti-aging due to its precursor role in hormone synthesis.

Basic Information

Product Name	Pregnenolone
CAS No.	145-13-1
Molecular Formula	C21H32O2
Molecular Weight	316.48 g/mol
Synonyms	3β-Hydroxy-5-pregnen-20-one; (3β)-3-Hydroxypregn-5-en-20-one; Pregn-5-en-3β-ol-20-one; 5-Pregnen-3β-ol-20-one; NSC 17256; δ5-Pregnenolone
EINECS	205-647-1

Quality Control

Our Pregnenolone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications. Certificates of Analysis (COA) detailing the results of tests such as HPLC, IR, and loss on drying are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Specific Rotation	+28° to +32° (c=1 in CHCl3)
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.