Description

[[[5-[2,4-dioxo-5-[(E)-3-[3-[2-[6-[5-(7-oxo-3-thia-6,8-diazabicyclo[3. 3.0]oct-2-yl)pentanoylamino]hexanoylamino]ethyldisulfanyl]propanoylami no]prop-1-enyl]pyrimidin-1-yl]-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-p hosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid is a complex, high-purity nucleotide analog derivative designed for advanced biochemical and pharmaceutical research. This compound is critical for its role as a potent and selective modulator of specific enzymatic pathways, offering researchers a precise tool for mechanistic studies. It is primarily utilized by pharmaceutical R&D teams and academic research institutions focused on developing novel therapeutics, particularly in the fields of antiviral and anticancer drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel nucleoside-based therapeutics.
• Antiviral Drug Discovery: Investigated for its mechanism of action against viral polymerases and replication enzymes.
• Oncology Research: Used in preclinical studies to evaluate its efficacy as a targeted agent against specific cancer cell lines.
• Biochemical Assay Development: Functions as a substrate or inhibitor in high-throughput screening (HTS) assays to identify new drug candidates.
• Enzymology Studies: Employed as a tool compound to study enzyme kinetics, inhibition, and structure-activity relationships (SAR).
• Proteomics and Molecular Biology: Can be used in the development of probes for studying nucleic acid metabolism and related cellular processes.

Basic Information

Product Name	[[[5-[2,4-dioxo-5-[(E)-3-[3-[2-[6-[5-(7-oxo-3-thia-6,8-diazabicyclo[3. 3.0]oct-2-yl)pentanoylamino]hexanoylamino]ethyldisulfanyl]propanoylami no]prop-1-enyl]pyrimidin-1-yl]-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-p hosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid
CAS No.	104142-46-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5'-O-[Hydroxy(phosphonooxy)phosphoryl]-3'-hydroxy-5-[5-[(1E)-3-[3-[2-[6-[[5-(7-oxo-3-thia-6,8-diazabicyclo[3.3.0]oct-2-yl)pentanoyl]amino]hexanoyl]amino]ethyldisulfanyl]propanoylamino]prop-1-en-1-yl]-2,4-dioxopyrimidin-1-yl]oxolane-2-carboxylic acid; Nucleotide Thia-diazabicyclo Derivative; Complex Nucleoside Phosphate Ester; Research Grade Nucleotide Analog; CAS 104142-46-3
EINECS	Contact for details

Quality Control

Our [[[5-[2,4-dioxo-5-[(E)-3-[3-[2-[6-[5-(7-oxo-3-thia-6,8-diazabicyclo[3. 3.0]oct-2-yl)pentanoylamino]hexanoylamino]ethyldisulfanyl]propanoylami no]prop-1-enyl]pyrimidin-1-yl]-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-p hosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and purity suitable for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥95.0%
Purity (HPLC)	≥98.0% (Area %)
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.