Description

[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate is a high-purity, complex nucleotide derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block or reference standard for studying enzymatic pathways, nucleotide metabolism, and the development of novel therapeutics. It is essential for researchers and manufacturers in the life sciences, biotechnology, and pharmaceutical sectors who require precise and reliable nucleotide analogs for their work.

Application

• Biochemical Research: Used as a substrate, inhibitor, or reference compound in enzymatic studies, particularly those involving kinases, polymerases, and other nucleotide-processing enzymes.
• Pharmaceutical R&D: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the development of antiviral, anticancer, or other nucleotide-based therapeutics.
• Diagnostic Reagent Manufacturing: Employed in the synthesis of probes, primers, or other components for molecular diagnostic kits and assays.
• Cell Culture & Metabolism Studies: Utilized to investigate cellular energy metabolism, signal transduction pathways, and the role of modified nucleotides in cellular function.
• Reference Standard: Provides a high-purity standard for quality control and analytical method development in pharmaceutical and biotechnology laboratories.
• Enzyme Mechanism Studies: Acts as a tool compound to elucidate the mechanisms of phosphotransfer and nucleotide recognition by various proteins.

Basic Information

Product Name	[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate
CAS No.	100849-67-0
Molecular Formula	C20H28N10O22P4
Molecular Weight	928.39 g/mol
Synonyms	P1,P4-Bis(5'-adenosyl) tetraphosphate, ammonium salt; Ap4A; Diadenosine 5',5'''-P1,P4-tetraphosphate; Adenosine(5')tetraphospho(5')adenosine; Diadenosine tetraphosphate; P1,P4-Di(adenosine-5') tetraphosphate; Adenosine 5'-tetraphosphate 5'-adenosine ester; Bis(5'-adenosyl) tetraphosphate
EINECS	Contact for details

Quality Control

Our [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.