Description

[(2S,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[hydroxy-[(2R,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-phosphoryl]oxy-phosphinic acid is a high-purity nucleotide derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound, with CAS No. 15839-74-4, serves as a critical building block and reference standard for studying enzymatic pathways, nucleotide metabolism, and cellular signaling. It is essential for research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in the development of novel therapeutics and molecular probes.

Application

• Biochemical Research: As a key intermediate or substrate in enzymatic studies, particularly those involving kinases, phosphatases, and other nucleotide-processing enzymes.
• Pharmaceutical Reference Standard: Used for the quality control and calibration of analytical methods (HPLC, LC-MS) in drug development pipelines targeting nucleotide-based pathways.
• Diagnostic Reagent Manufacturing: A vital component in the formulation of high-sensitivity assay kits for clinical diagnostics and life science research.
• Proteomics & Metabolomics: Employed in mass spectrometry-based studies to investigate cellular energy states and metabolic flux.
• Antiviral & Oncology Research: Potential precursor or analog in the synthesis and evaluation of novel nucleoside-based therapeutic candidates.
• Enzyme Cofactor Studies: Investigation of cofactor requirements and mechanisms in dehydrogenase and transferase reactions.

Basic Information

Product Name	[(2S,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[hydroxy-[(2R,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-phosphoryl]oxy-phosphinic acid
CAS No.	15839-74-4
Molecular Formula	C16H25N5O16P2
Molecular Weight	605.34 g/mol
Synonyms	Adenosine 5'-(trihydrogen diphosphate), 2'-(1-methyl-α-D-glucopyranuronosyl)-, (2'S)-; 2'-O-(α-D-Glucopyranosyluronic acid)adenosine 5'-diphosphate; ADP-2'-O-α-D-glucuronate; ADP-glucuronate; Adenosine 5'-diphosphate 2'-O-α-D-glucuronate; Adenosine-2'-diphosphoglucuronic acid; 2'-O-(α-D-Glucopyranosyluronic acid)-ADP
EINECS	Contact for details

Quality Control

Our production of this nucleotide derivative adheres to stringent quality management protocols to ensure batch-to-batch consistency and traceability. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (UV)	≥ 90.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.