Description

(13α,17S)-12α-[(2-Acetoxy-3-methyl-1-oxopentyl)oxy]-14β,15β:21,23-diepoxy-11β-formyloxy-7α-(2-hydroxy-3-methyl-1-oxobutoxy)-4,4,8-trimethyl-24-nor-5α-chola-1,20,22-trien-3-one is a complex, high-purity steroidal derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical advanced intermediate or reference standard for the synthesis and study of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and steroid-based drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based therapeutics.
• Reference Standard: Used in analytical method development and validation for quality control of related compounds.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity.
• Biochemical Research: Investigated for interactions with specific enzymes or receptors in steroid signaling pathways.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).
• Custom Synthesis: Starting material for the preparation of specialized derivatives for proprietary research programs.

Basic Information

Product Name	(13α,17S)-12α-[(2-Acetoxy-3-methyl-1-oxopentyl)oxy]-14β,15β:21,23-diepoxy-11β-formyloxy-7α-(2-hydroxy-3-methyl-1-oxobutoxy)-4,4,8-trimethyl-24-nor-5α-chola-1,20,22-trien-3-one
CAS No.	11052-31-6
Molecular Formula	C₃₈H₅₂O₁₂
Molecular Weight	700.82 g/mol
Synonyms	12α-(2-Acetoxy-3-methyl-1-oxopentyl)oxy-14β,15β:21,23-diepoxy-11β-formyloxy-7α-(2-hydroxy-3-methyl-1-oxobutoxy)-4,4,8-trimethyl-24-nor-5α-chola-1,20,22-trien-3-one; 24-Norchola-1,20,22-triene-3-one derivative; CAS 11052-31-6; Steroidal Epoxide Ester; 5α-Chola-1,20,22-trien-3-one, 12-[(2-acetoxy-3-methyl-1-oxopentyl)oxy]-14,15:21,23-diepoxy-11-(formyloxy)-7-[(2-hydroxy-3-methyl-1-oxobutyl)oxy]-4,4,8-trimethyl-, (5α,7α,11β,12α,13α,14β,15β,17S)-
EINECS	Contact for details

Quality Control

Our high-purity chemical intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from tests such as HPLC for assay and related substances, NMR, and mass spectrometry for structural confirmation. We support cGMP-compliant sourcing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.