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[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate CAS NO 10527-47-6


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CAS No.:10527-47-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate is a high-purity nucleotide derivative, essential for advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and research tool in the study of nucleic acid metabolism, enzyme mechanisms, and cellular signaling pathways. It is primarily required by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in nucleotide synthesis, antiviral research, and metabolic studies.

Application

  • Biochemical Research: As a key substrate or intermediate in enzymatic studies, particularly those involving kinases, polymerases, and other nucleotide-processing enzymes.
  • Pharmaceutical Development: Utilized in the research and synthesis of novel antiviral and anticancer nucleotide analogs.
  • Diagnostic Reagent Manufacturing: Serves as a critical component in the production of high-sensitivity assay kits for monitoring cellular energy status (e.g., ATP/ADP/AMP ratios) and related metabolic pathways.
  • Cell Culture & Metabolism Studies: Used to investigate the role of specific nucleotides in cell signaling, proliferation, and energy transfer mechanisms.
  • Enzyme Inhibitor Screening: Acts as a reference standard or target molecule in high-throughput screening for drug discovery programs.
  • Academic Research: Fundamental tool for universities and research institutes studying nucleic acid chemistry, bioenergetics, and molecular biology.

Basic Information

Item Details
Product Name [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate
CAS No. 10527-47-6
Molecular Formula C20H27N10O16P3
Molecular Weight 780.39 g/mol
Synonyms Adenosine 5'-(tetrahydrogen triphosphate); P1,P3-Di(adenosine-5') triphosphate; Diadenosine triphosphate; Ap3A; Diadenosine 5',5'''-P1,P3-triphosphate; Adenosine(5')triphospho(5')adenosine; 5'-Adenylyl triphospho-5'-adenosine; P(1),P(3)-Di(adenosine-5') triphosphate
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Quality Control

Our [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Solubility Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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