Description

D-Glucopyranose, 1-C-[4-Chloro-3-[(4-Ethoxyphenyl)Methyl]Phenyl]-2,3,4,6-Tetrakis-o-(Trimethylsilyl)- is a sophisticated, fully protected carbohydrate derivative, specifically a silylated C-aryl glucoside, designed for advanced synthetic applications. This compound is a critical high-purity synthetic intermediate that provides chemists with a stable, reactive handle for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in glycosidase inhibitor or metabolic modulator research.
• Glycochemistry & Glycobiology Research: Used to create complex carbohydrate analogs and probes for studying biological recognition processes.
• Advanced Organic Synthesis: Serves as a protected glycosyl donor or a chiral scaffold in multi-step syntheses of natural products and specialty chemicals.
• Medicinal Chemistry: Enables the exploration of structure-activity relationships (SAR) by introducing a modified sugar moiety into lead compounds.
• Chemical Biology Tool Development: Potential precursor for labeled sugars or affinity tags used in biochemical assays.
• Process Chemistry Development: Evaluated for scalable routes to target molecules requiring this specific protected carbohydrate unit.

Basic Information

Product Name	D-Glucopyranose, 1-C-[4-Chloro-3-[(4-Ethoxyphenyl)Methyl]Phenyl]-2,3,4,6-Tetrakis-o-(Trimethylsilyl)-
CAS No.	960494-15-9
Molecular Formula	C36H61ClO6Si4
Molecular Weight	753.66 g/mol
Synonyms	1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-2,3,4,6-tetrakis-O-(trimethylsilyl)-D-glucopyranose; 2,3,4,6-Tetra-O-trimethylsilyl-1-C-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucopyranose; Fully Silylated C-Aryl Glucoside; Per-O-trimethylsilyl C-Glycoside; TMS-Protected C-Aryl Glucopyranose; CAS 960494-15-9
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality-controlled conditions to ensure batch-to-batch consistency and high purity. Our quality assurance protocol includes comprehensive analytical characterization using techniques such as NMR, HPLC, and MS. A detailed Certificate of Analysis (COA) is provided with each batch, confirming identity, purity, and conformity to agreed specifications. We adhere to cGMP principles for production and documentation where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.