Description

Methanamine, n-[(4-Fluoro-2-Methylphenyl)Methylene]-1-(Trimethylsilyl)- (9Ci) is a specialized organosilicon compound featuring a trimethylsilyl-protected amine and a fluorinated aromatic imine structure. This unique molecular architecture makes it a valuable advanced intermediate in synthetic organic chemistry, particularly for constructing complex molecules where selective protection and fluorination are required. It is primarily utilized by pharmaceutical R&D and agrochemical laboratories engaged in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides where the fluorine atom and silyl group impart specific biological activity and stability.
• Material Science Research: Acts as a precursor for synthesizing specialty silicon-containing polymers or surface-modifying agents with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing complex heterocycles or as a protected amine synthon in multi-step synthetic sequences.
• Ligand and Catalyst Development: Potential use in the preparation of novel ligands for transition metal catalysis, leveraging the imine and silyl functionalities.

Basic Information

Product Name	Methanamine, n-[(4-Fluoro-2-Methylphenyl)Methylene]-1-(Trimethylsilyl)- (9Ci)
CAS No.	815630-75-2
Molecular Formula	C12H18FNSi
Molecular Weight	223.36 g/mol
Synonyms	N-[(4-Fluoro-2-methylphenyl)methylene]-1-(trimethylsilyl)methanamine; 1-[(4-Fluoro-2-methylphenyl)methylideneamino]-1-(trimethylsilyl)methane; (4-Fluoro-2-methylbenzylidene)(trimethylsilylmethyl)amine; N-((4-Fluoro-2-methylphenyl)methylene)-1-(trimethylsilyl)methanamine; Trimethylsilylmethyl 4-fluoro-2-methylbenzylideneamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to a cGMP-compliant quality management system for production and control, ensuring reliability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.