Description

Bis(Trimethylsilyl)Carbodiimide is a versatile organosilicon reagent primarily used as a silylating agent and a dehydrating agent in organic synthesis. Its core value lies in its ability to introduce the trimethylsilyl (TMS) group and activate various functional groups under mild conditions, facilitating complex molecule construction. This high-purity compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for developing active ingredients and novel polymers.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the silylation of alcohols, amines, and amides to protect functional groups or modify reactivity in multi-step drug synthesis.
• Peptide Chemistry: Employed as a coupling agent or dehydrating agent in the formation of peptide bonds, offering advantages in yield and purity.
• Polymer & Material Science: Used in the synthesis of specialized polyimides, polycarbodiimides, and other high-performance polymers where thermal stability and specific mechanical properties are required.
• Agrochemical Production: Facilitates the synthesis of complex herbicide and pesticide molecules through efficient silylation and condensation reactions.
• Silicon Chemistry: Serves as a fundamental building block for preparing other organosilicon compounds and modifying silicon-based surfaces or materials.
• Chemical Derivatization for Analysis: Used to derivative polar compounds for Gas Chromatography (GC) or Mass Spectrometry (MS) analysis, improving volatility and detection.

Basic Information

Product Name	Bis(Trimethylsilyl)Carbodiimide
CAS No.	1000-70-0
Molecular Formula	C7H18N2Si2
Molecular Weight	186.40 g/mol
Synonyms	1,3-Bis(trimethylsilyl)carbodiimide; N,N'-Bis(trimethylsilyl)carbodiimide; BTMSC; Bis(TMS)carbodiimide; Hexamethyldisilylcarbodiimide; TMSN=C=NTMS; Carbonyldiimidazole, 1,1'-(trimethylsilyl) deriv.; 1,1'-(Carbonyldiimino)bis(1,1,1-trimethylsilane)
EINECS	213-674-6

Quality Control

Our Bis(Trimethylsilyl)Carbodiimide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure it meets the high-purity standards demanded for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile and moisture-sensitive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.